Nootrogen Review – The Best Brain Support Supplement 2021

Nootrogen review

In this Nootrogen review, you’ll learn everything you need to learn about this best brain support supplement before you make your buying decision.

Nootrogen is the groundbreaking development in Nootropics stacks that requires no prescription.

Through extensive clinical studies, research has identified2 key natural compounds that when consumed together have remarkable effects on the brain and cognitive function.

Dimethylaminoethanol and L-Pyroglutamic Acid.

Just like the majority of my office, I’m a bit reliant on my coffee.

Okay, okay – I am definitely reliant on my coffee.

First coffee when I wake up (instant coffee, but it does the trick), second at work before 9:30 am, and third around midday, give or take a few extra cups depending on what I have scheduled for the day.

This shouldn’t be a problem… except for the fact that I don’t actually like coffee.

Don’t tell my colleagues!

It tastes bitter.

I have to add far too much sugar to tolerate the taste.

It makes my teeth feel ‘ick’.

I get jittery sometimes.

I hit a massive coffee low by the mid-afternoon.

The only reason I drink it is I feel it gives me a performance boost.

This all led to me wondering if I could support my mind in other, less temporary ways.

I found nootropic supplements when looking for something that can support cognition nutritionally while giving me an energy kick.

Nootrogen review

The Options (Nootrogen review)

Before I settled on nootropics, I definitely considered all of the options.

Here is a summary of what else you can consider and why I settled on nootropics.

Prescription meds

This was off the table for me as I do not have any medical condition that warrants prescription meds.

Instead, I am after nutritional support for cognition.

Taking something that was designed for treating some kind of disease is obviously a bad idea, and the performance benefits of stimulants – no matter how great – clearly won’t last an eight-hour workday.

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Drink more coffee / take energy supplements

I love caffeine hit just as much as the next person, however in this case more caffeine is not the answer.

Sure, caffeine is great for a quick hit of energy, however, I find it gives me the jitters and over the long-term, it actually seems to harm my concentration.

The energy-low that follows the caffeine-high is not ideal for staying on track.


It seems to me like nootropics are the way to go for someone in my position.

These supplements are designed to support cognitive function by providing nutrients that the brain needs to function optimally.

Nootrogen claims to be the ultimate nootropic supplement supporting cognition, energy, focus, and everyday stress.

The choice of ingredients seems smart – amino acids, vitamins, minerals and botanical extracts are all included, making it a really comprehensive formula.

I can see why it’s called the ultimate nootropic with such a broad-spectrum formula.

I’m a big fan of the bottle as well, you can tell it’s a quality product.

It has a sleek black label with shimmering gold accents, overall, it looks very smart.

It’s small enough to carry around in a handbag or leave in your desk drawer.

How does Nootrogen work?

Some nootropics on the market seemed to focus on high concentrations of one ingredient – eg. pure Panax ginseng or high-concentration choline.

I see this approach as a kind of dangerous as I haven’t been told by a doctor that I am deficient in anything in particular, and there can be ‘too much of a good thing’ with some nutrients anyhow.

I love that Nootrogen reads more like a multivitamin with many vitamins and minerals beneficial for brain support.

Nootropic ingredients are typically either synthetic or natural.

Synthetic nootropics use lab-processed extracts whereas natural and herbal nootropics use whole botanicals like

Panax ginseng root.

I can appreciate that Nootrogen uses a combination of modern lab-processed compounds as well as botanical extracts because that means purity, quality and reliability.

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Nootrogen Ingredients


When you succeed at something, you might say you aced it.

If you’re an expert at something, you might call yourself an ace.

So it goes that “ace” is strongly associated with success, just like acetylcholine is associated with cognitive success.

Or am I reading into it too much?

Acetylcholine is one of the most abundant neurotransmitters in the human body.

It is found in brain neurons and supports memory and cognition. Sadly, acetylcholine supplements don’t exist, however, acetylcholine levels can be supported through choline.

Of all the ingredients in Nootrogen, this one is my current favourite.

Choline is an essential nutrient needed by your body with vital importance for your brain.

Your body can make a little choline on its own, but not enough to keep you from becoming unwell.

Mostly this essential nutrient needs to be obtained through diet. Most people don’t get enough choline from the food they eat.[2]

Choline is a primary building block for the neurotransmitter acetylcholine. Some of the uses of choline include:

  • Memory: Increased choline intake supports memory function via the basal forebrain cholinergic system.[1]
  • Developing Brain Cells: Choline contributes to the process of neurogenesis, helping your brain develop and maintain brain cells.[3]
  • Brain Energy: Choline is thought to be essential to healthy cognitive performance in adults.[4]

Nootrogen includes choline bitartrate which is choline combined with tartaric acid.

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B Vitamins

Nootrogen contains nearly the full B-vitamin complex, including vitamin B1, B2, B3, B5, B6, B7, & B9. The B-group is often called the energy vitamins.[8]

These vitamins are needed to help the body use energy-yielding nutrients (carbohydrates, fat, protein) for fuel.

The brain is very hungry for energy.

It consumes about 20% of the body’s total energy reserves, but only accounts for 2% of an adult’s body weight![5]

So what happens when the tank is low?

Symptoms of brain fog and mental fatigue may surface when the brain is lacking fuel such as glucose, oxygen, fatty acids, or amino acids.

The best way to support brain energy is through better sleep and nutrition.

When given adequate nutrition through carbs, fats, and proteins, as well as a blend of B-Vitamins to help convert these into energy, the body and brain are supported to perform.

Essential antioxidants

One result of the brain being so hungry for energy is the production of free radicals.

It’s an unavoidable consequence for such a big, powerful, complex thinking organ.

These free radicals (oxidants) need to be kept under control, and that’s the role of vitamins C and E.

Putting it simply, vitamin C is the water-based antioxidant, and vitamin E is the oil-based antioxidant.

Both are essential to maintain a healthy brain. Nootrogen ticks both their boxes.[6]

Vitamin A also plays an important antioxidant role in the visual system (eyes and brain).


Occurring naturally in the brain, GABA attaches to proteins in your brain to produce a calming effect.

I have read some pretty mixed reviews on GABA for cognitive performance.

On the one hand, GABA supports everyday stress, so whether you are gaming, studying, or working an intense job, you could probably benefit from reduced stress!

Not to mention, many people struggle to concentrate and perform when under stress.

On the other hand, the calming effect of GABA may reduce concentration.

GABA apparently helps decrease beta brain waves. Decreased beta brain waves may decrease attention, alertness, concentration, and developing memories.

So how will GABA affect you? More concentration or less? Well, it depends.

If you are reaching for a nootropic in a stressful situation or have unbalanced GABA levels then the GABA generation may cause a decrease in stress and adrenaline.

In this situation, a decrease in stress may improve focus.

If you are reaching for a nootropic at a time when your body is producing melatonin (eg night time) or when you are very relaxed, a GABA nootropic may create a lack of concentration.


Glutamic Acid & Zinc

Nootrogen includes two pretty key ingredients relating to GABA.

Glutamic Acid is the precursor for the synthesis of GABA, and it’s right there in the Nootrogen Proprietary Blend.

Zinc helps the release of GABA from its receptors. Nootrogen supplies 91% of the recommended daily value of zinc in each serving.

Trace Minerals

I’ve read that Selenium is something that you don’t need much of, but it’s really important in the brain as a specialized antioxidant.

Chromium and boron are two more trace metals that the brain needs enough of to fulfil its potential.[6]

Phosphatidylserine (PS)

This phospholipid may be found in all cells however it is most highly concentrated in the brain.

Studies have shown that supplementing with this ingredient can support cognition, focus, memory, and recall.[9]

It does this in a few ways:

  • Memory formation through neuroplasticity: PS keeps brain cells fluid and neuroplastic, helps neurons form new connections to form memories. It also helps you stay sharp by easing the flow of glucose and oxygen needed to power brain cells.
  • Supporting neurotransmitters: PS is a vital part of the flow of neurotransmitters like dopamine and acetylcholine. PS also contains choline, a precursor to acetylcholine.

As for the other ingredients?

Well, there are a lot of them and more research is still needed.

DHA must be included to support the omega-3 fatty acids in the brain,[7] and vitamin D must be included to support both cognition and mood.

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Serving Size and Cautions

My personal opinion is that everyone should be paying attention to the needs of their brain, and the nutrition it requires.

Nutritionally speaking, that could mean regularly eating things like liver, L-tyrosine, choline, a range of nuts and seeds, fruit, green leafy veggies, fish, lean meats, and so on.

Taking a broad-spectrum nootropic supplement goes a long way towards that goal.

Nootrogen is a great all-rounder for nootropics.

There are 60 capsules in each bottle, this will last you 1-month when two pills are taken daily.

The capsules should be taken 20 – 30 minutes before a meal.

I personally prefer taking them before lunch as this is when I usually start to lose focus.

I find I feel the effects of Nootrogen right away and others on forums say the same.

My mileage might not necessarily be your mileage (YMMV).

How much does Nootrogen Cost?

Here’re the prices of this powerful supplement below;

  • 1 Bottle cost $29.95
  • 2 Bottles cost $52.96
  • 3 Bottles plus 1 free cost $78.96

If you change your mind about Nootrogen, unopened bottles can be returned for free.

So, I hope you get everything you want to learn about Nootrogen in this Nootrogen review?

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  • Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Food
    Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food
    Components for Operational Rations. Washington (DC): National Academies Press (US); 1994. 19,
    Choline: Human Requirements and Effects on Human Performance. Available from:

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